LIPID METABOLISM During EXERCISE
The Lipolytic pathway, picture taken from Exercise Nutrition by Jeffery Horowitz, PhD, p.99
‘Fat burn’ really occurs in three major stages, these stages are shown in the diagram to the left.
During exercise, the body releases epinephrine and norepinephrine, (catecholamines).
Catecholamines act as a catalyst to the entire lipolytic pathway, and sets fat burn into motion by binding to the beta receptors (see the ‘β’ in the diagram) on the cell membrane.
Once these beta receptors are stimulated, ATP is converted to cAMP. This converted cAMP uses it’s phosphate group to bind and remove perilipins from the surface of the triglyceride, and hormone sensitive lipase (HSL) is allowed to cause the release of lipids (fat) into the blood stream.
(Sztalryd and colleagues et al 2003, Souza and colleagues et al 1998)
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